Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

The molecular mechanisms underlying vascular inflammation and associated inflammatory vascular diseases are not well defined. Here we show that endothelial intracellular adenosine and its key regulator adenosine kinase (ADK) play important roles in vascular inflammation. Pro-inflammatory stimuli lea...

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Detalles Bibliográficos
Autores principales: Xu, Yiming, Wang, Yong, Yan, Siyuan, Yang, Qiuhua, Zhou, Yaqi, Zeng, Xianqiu, Liu, Zhiping, An, Xiaofei, Toque, Haroldo A., Dong, Zheng, Jiang, Xuejun, Fulton, David J., Weintraub, Neal L., Li, Qinkai, Bagi, Zsolt, Hong, Mei, Boison, Detlev, Wu, Chaodong, Huo, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643397/
https://www.ncbi.nlm.nih.gov/pubmed/29038540
http://dx.doi.org/10.1038/s41467-017-00986-7

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