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KCa3.1 Inhibition Switches the Astrocyte Phenotype during Astrogliosis Associated with Ischemic Stroke Via Endoplasmic Reticulum Stress and MAPK Signaling Pathways
Ischemic stroke is a devastating neurological disease that can initiate a phenotype switch in astrocytes. Reactive astrogliosis is a significant pathological feature of ischemic stroke and is accompanied by changes in gene expression, hypertrophied processes and proliferation. The intermediate-condu...
Autores principales: | Yu, Zhihua, Yi, Mengni, Wei, Tianjiao, Gao, Xiaoling, Chen, Hongzhuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643415/ https://www.ncbi.nlm.nih.gov/pubmed/29075181 http://dx.doi.org/10.3389/fncel.2017.00319 |
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