TRPA1–FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p

Recent evidence suggests that the ion channel TRPA1 is implicated in lung adenocarcinoma (LUAD), where its role and mechanism of action remain unknown. We have previously established that the membrane receptor FGFR2 drives LUAD progression through aberrant protein–protein interactions mediated via i...

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Detalles Bibliográficos
Autores principales: Berrout, Jonathan, Kyriakopoulou, Eleni, Moparthi, Lavanya, Hogea, Alexandra S., Berrout, Liza, Ivan, Cristina, Lorger, Mihaela, Boyle, John, Peers, Chris, Muench, Stephen, Gomez, Jacobo Elies, Hu, Xin, Hurst, Carolyn, Hall, Thomas, Umamaheswaran, Sujanitha, Wesley, Laura, Gagea, Mihai, Shires, Michael, Manfield, Iain, Knowles, Margaret A., Davies, Simon, Suhling, Klaus, Gonzalez, Yurema Teijeiro, Carragher, Neil, Macleod, Kenneth, Abbott, N. Joan, Calin, George A., Gamper, Nikita, Zygmunt, Peter M., Timsah, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643494/
https://www.ncbi.nlm.nih.gov/pubmed/29038531
http://dx.doi.org/10.1038/s41467-017-00983-w

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