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A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression

Indoleamine 2,3 dioxygenase-1 (IDO-1) is an enzyme in the kynurenine pathway which augments tumor-induced immune tolerance. Previous studies in childhood acute myeloid leukemia (AML) have shown a negative correlation of IDO-1 mRNA expression with outcomes. The aim of our study was to develop a pract...

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Detalles Bibliográficos
Autores principales:	Mangaonkar, Abhishek, Mondal, Ashis Kumar, Fulzule, Sadanand, Pundkar, Chetan, Park, Eun Jeong, Jillella, Anand, Kota, Vamsi, Xu, Hongyan, Savage, Natasha M., Shi, Huidong, Munn, David, Kolhe, Ravindra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643528/ https://www.ncbi.nlm.nih.gov/pubmed/29038460 http://dx.doi.org/10.1038/s41598-017-12940-0

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