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Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis

Phosphofructokinase 1 (PFK1) plays a critical role in glycolysis; however, its role and regulation in tumorigenesis are not well understood. Here, we demonstrate that PFK1 platelet isoform (PFKP) is the predominant PFK1 isoform in human glioblastoma cells and its expression correlates with total PFK...

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Detalles Bibliográficos
Autores principales:	Lee, Jong-Ho, Liu, Rui, Li, Jing, Zhang, Chuanbao, Wang, Yugang, Cai, Qingsong, Qian, Xu, Xia, Yan, Zheng, Yanhua, Piao, Yuji, Chen, Qianming, de Groot, John F., Jiang, Tao, Lu, Zhimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643558/ https://www.ncbi.nlm.nih.gov/pubmed/29038421 http://dx.doi.org/10.1038/s41467-017-00906-9

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