Targeting MET in cancer therapy

MET encodes a receptor tyrosine kinase c-MET for hepatocyte growth factor (HGF). The specific combination of c-MET and HGF activates downstream signaling pathways to trigger cell migration, proliferation, and angiogenesis. MET exon 14 alterations and MET gene amplification play a critical role in th...

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Detalles Bibliográficos
Autores principales: Mo, Hong-Nan, Liu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643781/
https://www.ncbi.nlm.nih.gov/pubmed/29063069
http://dx.doi.org/10.1016/j.cdtm.2017.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643781/
https://www.ncbi.nlm.nih.gov/pubmed/29063069
http://dx.doi.org/10.1016/j.cdtm.2017.06.002

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