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Obesity in individuals with schizophrenia: a case controlled study in Scotland

BACKGROUND: Despite extensive clinical concern about rates of obesity in patients with schizophrenia, there is little evidence of the extent of this problem at a population level. AIMS: To estimate levels of obesity in a national population sample by comparing patients with schizophrenia with matche...

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Autores principales: Cameron, Isobel M., Hamilton, Ross J., Fernie, Gordon, MacGillivray, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal College of Psychiatrists 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643876/
https://www.ncbi.nlm.nih.gov/pubmed/29093827
http://dx.doi.org/10.1192/bjpo.bp.116.003640
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author Cameron, Isobel M.
Hamilton, Ross J.
Fernie, Gordon
MacGillivray, Stephen A.
author_facet Cameron, Isobel M.
Hamilton, Ross J.
Fernie, Gordon
MacGillivray, Stephen A.
author_sort Cameron, Isobel M.
collection PubMed
description BACKGROUND: Despite extensive clinical concern about rates of obesity in patients with schizophrenia, there is little evidence of the extent of this problem at a population level. AIMS: To estimate levels of obesity in a national population sample by comparing patients with schizophrenia with matched controls. METHOD: We calculated levels of obesity for each patient with schizophrenia from the national Primary Care Clinical Informatics Unit database (n=4658) matched with age, gender and neighbourhood controls. RESULTS: We demonstrated a significant increased obesity hazard for the schizophrenia group using Cox regression analysis, with odds ratio (OR) of 1.94 (95% CI 1.81–2.10) (under the assumption of missing body mass index (BMI) indicating non-obesity) and OR=1.68 (95% CI 1.55–1.81) where no assumptions were made for missing BMI data. CONCLUSIONS: People with schizophrenia are at increased risk of being obese compared with controls matched by age, gender and practice attended. Priority should be given to research which aims to reduce weight and increase activity in those with schizophrenia. DECLARATION OF INTEREST: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.
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spelling pubmed-56438762017-11-01 Obesity in individuals with schizophrenia: a case controlled study in Scotland Cameron, Isobel M. Hamilton, Ross J. Fernie, Gordon MacGillivray, Stephen A. BJPsych Open Short Report BACKGROUND: Despite extensive clinical concern about rates of obesity in patients with schizophrenia, there is little evidence of the extent of this problem at a population level. AIMS: To estimate levels of obesity in a national population sample by comparing patients with schizophrenia with matched controls. METHOD: We calculated levels of obesity for each patient with schizophrenia from the national Primary Care Clinical Informatics Unit database (n=4658) matched with age, gender and neighbourhood controls. RESULTS: We demonstrated a significant increased obesity hazard for the schizophrenia group using Cox regression analysis, with odds ratio (OR) of 1.94 (95% CI 1.81–2.10) (under the assumption of missing body mass index (BMI) indicating non-obesity) and OR=1.68 (95% CI 1.55–1.81) where no assumptions were made for missing BMI data. CONCLUSIONS: People with schizophrenia are at increased risk of being obese compared with controls matched by age, gender and practice attended. Priority should be given to research which aims to reduce weight and increase activity in those with schizophrenia. DECLARATION OF INTEREST: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license. The Royal College of Psychiatrists 2017-10-17 /pmc/articles/PMC5643876/ /pubmed/29093827 http://dx.doi.org/10.1192/bjpo.bp.116.003640 Text en © 2017 The Royal College of Psychiatrists http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Report
Cameron, Isobel M.
Hamilton, Ross J.
Fernie, Gordon
MacGillivray, Stephen A.
Obesity in individuals with schizophrenia: a case controlled study in Scotland
title Obesity in individuals with schizophrenia: a case controlled study in Scotland
title_full Obesity in individuals with schizophrenia: a case controlled study in Scotland
title_fullStr Obesity in individuals with schizophrenia: a case controlled study in Scotland
title_full_unstemmed Obesity in individuals with schizophrenia: a case controlled study in Scotland
title_short Obesity in individuals with schizophrenia: a case controlled study in Scotland
title_sort obesity in individuals with schizophrenia: a case controlled study in scotland
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643876/
https://www.ncbi.nlm.nih.gov/pubmed/29093827
http://dx.doi.org/10.1192/bjpo.bp.116.003640
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