Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma

BACKGROUND: Recent studies have identified age-related changes in DNA methylation patterns in normal and cancer tissues in a process that is called epigenetic drift. However, the evolving patterns, functional consequences, and dynamics of epigenetic drift during carcinogenesis remain largely unexplo...

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Detalles Bibliográficos
Autores principales: Luebeck, E. Georg, Curtius, Kit, Hazelton, William D., Maden, Sean, Yu, Ming, Thota, Prashanthi N., Patil, Deepa T., Chak, Amitabh, Willis, Joseph E., Grady, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644061/
https://www.ncbi.nlm.nih.gov/pubmed/29046735
http://dx.doi.org/10.1186/s13148-017-0409-4

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