Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

BACKGROUND: Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously, we have shown that only Th1 but...

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Detalles Bibliográficos
Autores principales: Prajeeth, Chittappen K., Kronisch, Julius, Khorooshi, Reza, Knier, Benjamin, Toft-Hansen, Henrik, Gudi, Viktoria, Floess, Stefan, Huehn, Jochen, Owens, Trevor, Korn, Thomas, Stangel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644084/
https://www.ncbi.nlm.nih.gov/pubmed/29037246
http://dx.doi.org/10.1186/s12974-017-0978-3

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