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Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure
BACKGROUND: Accurate inference of genetic ancestry is of fundamental interest to many biomedical, forensic, and anthropological research areas. Genetic ancestry memberships may relate to genetic disease risks. In a genome association study, failing to account for differences in genetic ancestry betw...
Autores principales: | Byun, Jinyoung, Han, Younghun, Gorlov, Ivan P., Busam, Jonathan A., Seldin, Michael F., Amos, Christopher I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644186/ https://www.ncbi.nlm.nih.gov/pubmed/29037167 http://dx.doi.org/10.1186/s12864-017-4166-8 |
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