Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms

Background: Cardiomyocyte progenitor cells (CMPCs) are a promising cell source for regenerative cell therapy to improve cardiac function after myocardial infarction. However, it is unknown whether undifferentiated CMPCs have arrhythmogenic risks. We investigate whether undifferentiated, regionally a...

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Detalles Bibliográficos
Autores principales: Smit, Nicoline W., Cócera Ortega, Lucia, Végh, Anna M. D., Meijborg, Veronique M. F., Smits, Anke M., Klerk, Mischa, Tijsen, Anke J. M., Tan, Hanno L., Goumans, Marie-José H. T., Boink, Gerard J. J., Coronel, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644204/
https://www.ncbi.nlm.nih.gov/pubmed/29075204
http://dx.doi.org/10.3389/fphys.2017.00797

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