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Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment

BACKGROUND: Brain metastases are common in patients with metastatic melanoma. With increasing numbers of melanoma patients on anti-PD-1 therapy, we sought to evaluate the safety and initial response of brain metastases treated with concurrent pembrolizumab and radiation therapy. METHODS: From an ins...

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Detalles Bibliográficos
Autores principales: Anderson, Erik S., Postow, Michael A., Wolchok, Jedd D., Young, Robert J., Ballangrud, Åse, Chan, Timothy A., Yamada, Yoshiya, Beal, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644249/
https://www.ncbi.nlm.nih.gov/pubmed/29037215
http://dx.doi.org/10.1186/s40425-017-0282-x