Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition

BACKGROUND: Pulmonary fibrosis is a late manifestation of acute respiratory distress syndrome (ARDS). Sepsis is a major cause of ARDS, and its pathogenesis includes endotoxin-induced vascular injury. Recently, endothelial-to-mesenchymal transition (EndMT) was shown to play an important role in pulmo...

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Detalles Bibliográficos
Autores principales: Suzuki, Toshio, Tada, Yuji, Gladson, Santhi, Nishimura, Rintaro, Shimomura, Iwao, Karasawa, Satoshi, Tatsumi, Koichiro, West, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644255/
https://www.ncbi.nlm.nih.gov/pubmed/29037205
http://dx.doi.org/10.1186/s12931-017-0660-4

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