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Propofol produces preventive analgesia via GluN2B-containing NMDA receptor/ERK1/2 signaling pathway in a rat model of inflammatory pain

Propofol, an intravenous anesthetic, has been shown to offer superior analgesic effect clinically. Whether propofol has preventive analgesic property remains unexplored. The present study investigated the antinociceptive effect of propofol and underlying molecular and cellular mechanisms via pre-emp...

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Detalles Bibliográficos
Autores principales: Qiu, Qiu, Sun, Liting, Wang, Xiao Min, Lo, Amy CY, Wong, Kar Lok, Gu, Pan, Wong, Sau Ching Stanley, Cheung, Chi Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644366/
https://www.ncbi.nlm.nih.gov/pubmed/28969472
http://dx.doi.org/10.1177/1744806917737462