Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria

We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led...

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Autores principales: Aboderin, Oladipo A., Adefehinti, Olufemi, Odetoyin, Babatunde W., Olotu, Amadin A., Okeke, Iruka N., Adeodu, Olugbenga O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS OpenJournals 2012
Materias:
Case Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644516/
https://www.ncbi.nlm.nih.gov/pubmed/29062733
http://dx.doi.org/10.4102/ajlm.v1i1.16
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author Aboderin, Oladipo A.
Adefehinti, Olufemi
Odetoyin, Babatunde W.
Olotu, Amadin A.
Okeke, Iruka N.
Adeodu, Olugbenga O.
author_facet Aboderin, Oladipo A.
Adefehinti, Olufemi
Odetoyin, Babatunde W.
Olotu, Amadin A.
Okeke, Iruka N.
Adeodu, Olugbenga O.
author_sort Aboderin, Oladipo A.
collection PubMed
description We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led to sustained resolution of fever. Resource-limited hospitals can incur prohibitive costs from ESBL-producer infections because of diagnostic limitations and consequent treatment failure involving prolonged supportive therapy.
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spelling pubmed-56445162017-10-23 Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria Aboderin, Oladipo A. Adefehinti, Olufemi Odetoyin, Babatunde W. Olotu, Amadin A. Okeke, Iruka N. Adeodu, Olugbenga O. Afr J Lab Med Case Studies We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led to sustained resolution of fever. Resource-limited hospitals can incur prohibitive costs from ESBL-producer infections because of diagnostic limitations and consequent treatment failure involving prolonged supportive therapy. AOSIS OpenJournals 2012-06-04 /pmc/articles/PMC5644516/ /pubmed/29062733 http://dx.doi.org/10.4102/ajlm.v1i1.16 Text en © 2012. The Authors https://creativecommons.org/licenses/by/4.0/ Licensee: AOSIS OpenJournals. This work is licensed under the Creative Commons Attribution License.
spellingShingle Case Studies
Aboderin, Oladipo A.
Adefehinti, Olufemi
Odetoyin, Babatunde W.
Olotu, Amadin A.
Okeke, Iruka N.
Adeodu, Olugbenga O.
Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria
title Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria
title_full Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria
title_fullStr Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria
title_full_unstemmed Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria
title_short Prolonged febrile illness due to CTX-M-15 extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection in Nigeria
title_sort prolonged febrile illness due to ctx-m-15 extended-spectrum β-lactamase-producing klebsiella pneumoniae infection in nigeria
topic Case Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644516/
https://www.ncbi.nlm.nih.gov/pubmed/29062733
http://dx.doi.org/10.4102/ajlm.v1i1.16
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