Cargando…

GBPs Inhibit Motility of Shigella flexneri but Are Targeted for Degradation by the Bacterial Ubiquitin Ligase IpaH9.8

Interferon exposure boosts cell-autonomous immunity for more efficient pathogen control. But how interferon-enhanced immunity protects the cytosol against bacteria and how professionally cytosol-dwelling bacteria avoid clearance are insufficiently understood. Here we demonstrate that the interferon-...

Descripción completa

Detalles Bibliográficos
Autores principales: Wandel, Michal P., Pathe, Claudio, Werner, Emma I., Ellison, Cara J., Boyle, Keith B., von der Malsburg, Alexander, Rohde, John, Randow, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644667/
https://www.ncbi.nlm.nih.gov/pubmed/29024643
http://dx.doi.org/10.1016/j.chom.2017.09.007