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Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients

AIMS: To compare effectiveness of a 1-year weight loss program in moderately and severely obese patients. METHODS: The study sample included 311 obese patients participating in a weight loss program, which comprised a 12-week weight reduction phase (low-calorie formula diet) and a 40-week weight mai...

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Autores principales: Winkler, Julia K., Schultz, Jobst-Hendrik, Woehning, Annika, Piel, David, Gartner, Lena, Hildebrand, Mirjam, Roeder, Eva, Nawroth, Peter P., Wolfrum, Christian, Rudofsky, Gottfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger GmbH 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644682/
https://www.ncbi.nlm.nih.gov/pubmed/24135973
http://dx.doi.org/10.1159/000355822
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author Winkler, Julia K.
Schultz, Jobst-Hendrik
Woehning, Annika
Piel, David
Gartner, Lena
Hildebrand, Mirjam
Roeder, Eva
Nawroth, Peter P.
Wolfrum, Christian
Rudofsky, Gottfried
author_facet Winkler, Julia K.
Schultz, Jobst-Hendrik
Woehning, Annika
Piel, David
Gartner, Lena
Hildebrand, Mirjam
Roeder, Eva
Nawroth, Peter P.
Wolfrum, Christian
Rudofsky, Gottfried
author_sort Winkler, Julia K.
collection PubMed
description AIMS: To compare effectiveness of a 1-year weight loss program in moderately and severely obese patients. METHODS: The study sample included 311 obese patients participating in a weight loss program, which comprised a 12-week weight reduction phase (low-calorie formula diet) and a 40-week weight maintenance phase. Body weight and glucose and lipid values were determined at the beginning of the program as well as after the weight reduction and the weight maintenance phase. Participants were analyzed according to their BMI class at baseline (30-34.9 kg/m(2); 35-39.9 kg/m(2); 40-44.9 kg/m(2); 45-49.9 kg/m(2); ≥50 kg/m(2)). Furthermore, moderately obese patients (BMI ℋ 40 kg/m(2)) were compared to severely obese participants (BMI ≥ 40 kg/m(2)). RESULTS: Out of 311 participants, 217 individuals completed the program. Their mean baseline BMI was 41.8 ± 0.5 kg/m(2). Average weight loss was 17.9 ± 0.6%, resulting in a BMI of 34.3 ± 0.4 kg/m(2) after 1 year (p ℋ 0.001). Overall weight loss was not significantly different in moderately and severely obese participants. Yet, severely obese participants achieved greater weight loss during the weight maintenance phase than moderately obese participants (−3.1 ± 0.7% vs. −1.2 ± 0.6%; p = 0.04). Improvements in lipid profiles and glucose metabolism were found throughout all BMI classes. CONCLUSION: 1-year weight loss intervention improves body weight as well as lipid and glucose metabolism not only in moderately, but also in severely obese individuals.
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spelling pubmed-56446822017-12-04 Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients Winkler, Julia K. Schultz, Jobst-Hendrik Woehning, Annika Piel, David Gartner, Lena Hildebrand, Mirjam Roeder, Eva Nawroth, Peter P. Wolfrum, Christian Rudofsky, Gottfried Obes Facts Original Article AIMS: To compare effectiveness of a 1-year weight loss program in moderately and severely obese patients. METHODS: The study sample included 311 obese patients participating in a weight loss program, which comprised a 12-week weight reduction phase (low-calorie formula diet) and a 40-week weight maintenance phase. Body weight and glucose and lipid values were determined at the beginning of the program as well as after the weight reduction and the weight maintenance phase. Participants were analyzed according to their BMI class at baseline (30-34.9 kg/m(2); 35-39.9 kg/m(2); 40-44.9 kg/m(2); 45-49.9 kg/m(2); ≥50 kg/m(2)). Furthermore, moderately obese patients (BMI ℋ 40 kg/m(2)) were compared to severely obese participants (BMI ≥ 40 kg/m(2)). RESULTS: Out of 311 participants, 217 individuals completed the program. Their mean baseline BMI was 41.8 ± 0.5 kg/m(2). Average weight loss was 17.9 ± 0.6%, resulting in a BMI of 34.3 ± 0.4 kg/m(2) after 1 year (p ℋ 0.001). Overall weight loss was not significantly different in moderately and severely obese participants. Yet, severely obese participants achieved greater weight loss during the weight maintenance phase than moderately obese participants (−3.1 ± 0.7% vs. −1.2 ± 0.6%; p = 0.04). Improvements in lipid profiles and glucose metabolism were found throughout all BMI classes. CONCLUSION: 1-year weight loss intervention improves body weight as well as lipid and glucose metabolism not only in moderately, but also in severely obese individuals. S. Karger GmbH 2013-10 2013-10-11 /pmc/articles/PMC5644682/ /pubmed/24135973 http://dx.doi.org/10.1159/000355822 Text en Copyright © 2013 by S. Karger GmbH, Freiburg http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable tothe online version of the article only. Distribution permitted for non-commercial purposes only.
spellingShingle Original Article
Winkler, Julia K.
Schultz, Jobst-Hendrik
Woehning, Annika
Piel, David
Gartner, Lena
Hildebrand, Mirjam
Roeder, Eva
Nawroth, Peter P.
Wolfrum, Christian
Rudofsky, Gottfried
Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients
title Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients
title_full Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients
title_fullStr Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients
title_full_unstemmed Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients
title_short Effectiveness of a Low-Calorie Weight Loss Program in Moderately and Severely Obese Patients
title_sort effectiveness of a low-calorie weight loss program in moderately and severely obese patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644682/
https://www.ncbi.nlm.nih.gov/pubmed/24135973
http://dx.doi.org/10.1159/000355822
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