Epithelial-Cell-Derived Phospholipase A(2) Group 1B Is an Endogenous Anthelmintic

Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A(2) group 1B (PLA(2)g1B) as a host-derived endogenous anthelmintic. PLA(2)g1B is elevated in resistant m...

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Detalles Bibliográficos
Autores principales: Entwistle, Lewis J., Pelly, Victoria S., Coomes, Stephanie M., Kannan, Yashaswini, Perez-Lloret, Jimena, Czieso, Stephanie, Silva dos Santos, Mariana, MacRae, James I., Collinson, Lucy, Sesay, Abdul, Nikolov, Nikolay, Metidji, Amina, Helmby, Helena, Hui, David Y., Wilson, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644720/
https://www.ncbi.nlm.nih.gov/pubmed/29024642
http://dx.doi.org/10.1016/j.chom.2017.09.006

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