Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy

Chronic hepatitis C virus (HCV) infection results in sustained immune activation in both the periphery and hepatic tissue. HCV infection induces innate immune signaling that is responsible for recognition of dsRNA, leading to activation of transcription factors and production of Type I and III IFNs,...

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Detalles Bibliográficos
Autores principales: Burchill, Matthew A., Roby, Justin A., Crochet, Nanette, Wind-Rotolo, Megan, Stone, Amy E., Edwards, Michael G., Dran, Rachael J., Kriss, Michael S., Gale, Michael, Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645093/
https://www.ncbi.nlm.nih.gov/pubmed/29040318
http://dx.doi.org/10.1371/journal.pone.0186213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645093/
https://www.ncbi.nlm.nih.gov/pubmed/29040318
http://dx.doi.org/10.1371/journal.pone.0186213

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