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Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model

We investigated the effects of a vibratory stimulus on the plantar surface of the hind limb for motor, sensory, and locomotive function using a mouse cast model. The right knee joint of C57BL/6 male mice (7 weeks, 20 g, n = 31) was flexed with aluminum splint and tape for 6 weeks. These mice were ra...

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Autores principales: Doi, Atsushi, Miyamoto, Kazuaki, Nakano, Yu-shin, Sakasaki, Juntaro, Kasae, Syota, Nishimura, Keisuke, Shin, Min-Chul, Yoshimura, Megumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645094/
https://www.ncbi.nlm.nih.gov/pubmed/29040289
http://dx.doi.org/10.1371/journal.pone.0186189
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author Doi, Atsushi
Miyamoto, Kazuaki
Nakano, Yu-shin
Sakasaki, Juntaro
Kasae, Syota
Nishimura, Keisuke
Shin, Min-Chul
Yoshimura, Megumu
author_facet Doi, Atsushi
Miyamoto, Kazuaki
Nakano, Yu-shin
Sakasaki, Juntaro
Kasae, Syota
Nishimura, Keisuke
Shin, Min-Chul
Yoshimura, Megumu
author_sort Doi, Atsushi
collection PubMed
description We investigated the effects of a vibratory stimulus on the plantar surface of the hind limb for motor, sensory, and locomotive function using a mouse cast model. The right knee joint of C57BL/6 male mice (7 weeks, 20 g, n = 31) was flexed with aluminum splint and tape for 6 weeks. These mice were randomly divided into 2 groups (control group, n = 11 and vibration group, n = 12). The mice in the vibration group received vibration on the sole of the ankle for 15 minutes per day, 5 days per week. After the knee joint cast was removed, we measured the range of motion (ROM) of both knee and ankle joints and the sensory threshold of the sole. Further, both walking and swimming movements were analyzed with a digital video. The sole vibration did not affect the passive ROM of the knee joint and sensory threshold after cast removal. However, it increased the ankle dorsiflexion range and improved free walking, swimming, and active movement of the knee joint. In conclusion, we show that the vibration recovered both walking and swimming movements, which resulted from improvements in both the passive ankle dorsiflexion and active knee movement.
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spelling pubmed-56450942017-10-30 Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model Doi, Atsushi Miyamoto, Kazuaki Nakano, Yu-shin Sakasaki, Juntaro Kasae, Syota Nishimura, Keisuke Shin, Min-Chul Yoshimura, Megumu PLoS One Research Article We investigated the effects of a vibratory stimulus on the plantar surface of the hind limb for motor, sensory, and locomotive function using a mouse cast model. The right knee joint of C57BL/6 male mice (7 weeks, 20 g, n = 31) was flexed with aluminum splint and tape for 6 weeks. These mice were randomly divided into 2 groups (control group, n = 11 and vibration group, n = 12). The mice in the vibration group received vibration on the sole of the ankle for 15 minutes per day, 5 days per week. After the knee joint cast was removed, we measured the range of motion (ROM) of both knee and ankle joints and the sensory threshold of the sole. Further, both walking and swimming movements were analyzed with a digital video. The sole vibration did not affect the passive ROM of the knee joint and sensory threshold after cast removal. However, it increased the ankle dorsiflexion range and improved free walking, swimming, and active movement of the knee joint. In conclusion, we show that the vibration recovered both walking and swimming movements, which resulted from improvements in both the passive ankle dorsiflexion and active knee movement. Public Library of Science 2017-10-17 /pmc/articles/PMC5645094/ /pubmed/29040289 http://dx.doi.org/10.1371/journal.pone.0186189 Text en © 2017 Doi et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Doi, Atsushi
Miyamoto, Kazuaki
Nakano, Yu-shin
Sakasaki, Juntaro
Kasae, Syota
Nishimura, Keisuke
Shin, Min-Chul
Yoshimura, Megumu
Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
title Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
title_full Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
title_fullStr Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
title_full_unstemmed Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
title_short Sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
title_sort sole vibration improves locomotion through the recovery of joint movements in a mouse cast model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645094/
https://www.ncbi.nlm.nih.gov/pubmed/29040289
http://dx.doi.org/10.1371/journal.pone.0186189
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