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A novel LRP1-binding peptide L57 that crosses the blood brain barrier
The blood-brain barrier (BBB) is a major obstacle to drug delivery into the central nervous system (CNS), in particular for macromolecules such as peptides and proteins. However, certain macromolecules can reach the CNS via a receptor-mediated transcytosis (RMT) pathway, and low-density lipoprotein...
Autores principales: | Sakamoto, Kotaro, Shinohara, Tokuyuki, Adachi, Yusuke, Asami, Taiji, Ohtaki, Tetsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645116/ https://www.ncbi.nlm.nih.gov/pubmed/29090274 http://dx.doi.org/10.1016/j.bbrep.2017.07.003 |
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