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Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)
We explore potential dysregulation of macrophage phenotypes in COPD pathogenesis through integrated study of human small airway tissue, bronchoalveolar lavage (BAL) and an experimental murine model of COPD. We evaluated human airway tissue and BAL from healthy controls, normal lung function smokers...
Autores principales: | Eapen, Mathew Suji, Hansbro, Philip M., McAlinden, Kielan, Kim, Richard Y., Ward, Chris, Hackett, Tillie-Louise, Walters, Eugene H., Sohal, Sukhwinder Singh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645352/ https://www.ncbi.nlm.nih.gov/pubmed/29042607 http://dx.doi.org/10.1038/s41598-017-13888-x |
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