Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptide

ABCG4 is an ATP-binding cassette transmembrane protein which has been shown, in vitro, to participate in the cellular efflux of desmosterol and amyloid-β peptide (Aβ). ABCG4 is highly expressed in the brain, but its localization and function at the blood-brain barrier (BBB) level remain unknown. We...

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Detalles Bibliográficos
Autores principales: Dodacki, Agnès, Wortman, Matthew, Saubaméa, Bruno, Chasseigneaux, Stéphanie, Nicolic, Sophie, Prince, Nathalie, Lochus, Murielle, Raveu, Anne-Laure, Declèves, Xavier, Scherrmann, Jean-Michel, Patel, Shailendra B., Bourasset, Fanchon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645361/
https://www.ncbi.nlm.nih.gov/pubmed/29042617
http://dx.doi.org/10.1038/s41598-017-13750-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645361/
https://www.ncbi.nlm.nih.gov/pubmed/29042617
http://dx.doi.org/10.1038/s41598-017-13750-0

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