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GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment

Pancreatic cancer is one of the most lethal human cancers that currently does not have effective therapies. Novel treatments including nanomedicines and combination therapies are thus urgently needed for these types of deadly diseases. A key feature of pancreatic cancer is its tumor protective dense...

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Detalles Bibliográficos
Autores principales: Zhou, Quan, Zhou, Yongcun, Liu, Xiangrui, Shen, Youqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645386/
https://www.ncbi.nlm.nih.gov/pubmed/29042665
http://dx.doi.org/10.1038/s41598-017-13869-0