Cargando…
GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment
Pancreatic cancer is one of the most lethal human cancers that currently does not have effective therapies. Novel treatments including nanomedicines and combination therapies are thus urgently needed for these types of deadly diseases. A key feature of pancreatic cancer is its tumor protective dense...
Autores principales: | Zhou, Quan, Zhou, Yongcun, Liu, Xiangrui, Shen, Youqing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645386/ https://www.ncbi.nlm.nih.gov/pubmed/29042665 http://dx.doi.org/10.1038/s41598-017-13869-0 |
Ejemplares similares
-
Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms
por: Singh, Brahma N., et al.
Publicado: (2011) -
Effect of the sonic hedgehog inhibitor GDC-0449 on an in vitro isogenic cellular model simulating odontogenic keratocysts
por: Zhai, Jiemei, et al.
Publicado: (2019) -
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors
por: Benvenuto, Monica, et al.
Publicado: (2016) -
GDC respond to crisis
Publicado: (2020) -
Mentoring, performance and the GDC
por: Saw, Mabel, et al.
Publicado: (2021)