Extrafollicular CD4(+) T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Chronic graft-versus-host disease (cGVHD) is an autoimmune-like syndrome mediated by pathogenic CD4(+) T and B cells, but the function of extrafollicular and germinal center CD4(+) T and B interactions in cGVHD pathogenesis remains largely unknown. Here we show that extrafollicular CD4(+) T and B in...

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Detalles Bibliográficos
Autores principales: Deng, Ruishu, Hurtz, Christian, Song, Qingxiao, Yue, Chanyu, Xiao, Gang, Yu, Hua, Wu, Xiwei, Muschen, Markus, Forman, Stephen, Martin, Paul J., Zeng, Defu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645449/
https://www.ncbi.nlm.nih.gov/pubmed/29042531
http://dx.doi.org/10.1038/s41467-017-00880-2

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