A case of dedifferentiated liposarcoma of the heart and stomach

INTRODUCTION: Liposarcoma of the heart and stomach is rare. PRESENTAION OF CASE: We report a case of liposarcoma in both organs with dedifferentiated histology. A patient was referred to our hospital with anorexia and weight loss. Upper gastrointestinal tract endoscopy revealed 5–10-mm elevated lesions, and echocardiography and computed tomography showed tumorous lesions in the left atrium. Tumor resection and mitral valve replacement were performed, and biopsy was performed for the gastric tumor. Both the tumors were diagnosed as dedifferentiated liposarcoma. DISCUSSION: Liposarcoma – a mesenchymal malignant tumor that contains lipoblasts – is the second most common soft tissue sarcoma. The tumor occurs most frequently in the limbs and retroperitoneum and rarely originates in the heart and the stomach. CONCLUSION: Chemotherapy and radiotherapy are only adjunctive therapies but not es as standard treatment for cardiac tumors. Therefore, we believe that wide surgical resection was the best choice of treatment in the present case.