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Deletion of the Mineralocorticoid Receptor in Myeloid Cells Attenuates Central Nervous System Autoimmunity
Myeloid cells play an important role in the pathogenesis of multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Monocytes, macrophages, and microglia can adopt two distinct phenotypes, with M1-polarized cells being more related to inflammation and autoimmuni...
Autores principales: | Montes-Cobos, Elena, Schweingruber, Nils, Li, Xiao, Fischer, Henrike J., Reichardt, Holger M., Lühder, Fred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645513/ https://www.ncbi.nlm.nih.gov/pubmed/29081780 http://dx.doi.org/10.3389/fimmu.2017.01319 |
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