Topical Coenzyme Q10 demonstrates mitochondrial-mediated neuroprotection in a rodent model of ocular hypertension

Coenzyme Q10 (CoQ10) is a mitochondrial-targeted antioxidant with known neuroprotective activity. Its ocular effects when co-solubilised with α–tocopherol polyethylene glycol succinate (TPGS) were evaluated. In vitro studies confirmed that CoQ10 was significantly protective in different retinal gang...

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Detalles Bibliográficos
Autores principales: Davis, Benjamin Michael, Tian, Kailin, Pahlitzsch, Milena, Brenton, Jonathan, Ravindran, Nivedita, Butt, Gibran, Malaguarnera, Giulia, Normando, Eduardo M., Guo, Li, Cordeiro, M. Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645575/
https://www.ncbi.nlm.nih.gov/pubmed/28549843
http://dx.doi.org/10.1016/j.mito.2017.05.010

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