Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence

BACKGROUND: Altered expression of mRNA splicing factors occurs with ageing in vivo and is thought to be an ageing mechanism. The accumulation of senescent cells also occurs in vivo with advancing age and causes much degenerative age-related pathology. However, the relationship between these two proc...

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Detalles Bibliográficos
Autores principales: Latorre, Eva, Birar, Vishal C., Sheerin, Angela N., Jeynes, J. Charles C., Hooper, Amy, Dawe, Helen R., Melzer, David, Cox, Lynne S., Faragher, Richard G. A., Ostler, Elizabeth L., Harries, Lorna W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645932/
https://www.ncbi.nlm.nih.gov/pubmed/29041897
http://dx.doi.org/10.1186/s12860-017-0147-7

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