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Review on Research about Traditional Chinese Medicine in Cancer Stem Cell

Cancer stem cells (CSCs) are small subpopulations of neoplastic cells within a tumor, which have self-renewal and differentiation abilities and could generate new tumors with few cells. Researches have showed that CSCs are considered the most likely reason for cancer recurrence and metastasis. Accum...

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Detalles Bibliográficos
Autores principales: Wang, Yaohan, Feng, Li, Piao, Bingkui, Zhang, Peitong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646331/
https://www.ncbi.nlm.nih.gov/pubmed/29234398
http://dx.doi.org/10.1155/2017/4505194
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author Wang, Yaohan
Feng, Li
Piao, Bingkui
Zhang, Peitong
author_facet Wang, Yaohan
Feng, Li
Piao, Bingkui
Zhang, Peitong
author_sort Wang, Yaohan
collection PubMed
description Cancer stem cells (CSCs) are small subpopulations of neoplastic cells within a tumor, which have self-renewal and differentiation abilities and could generate new tumors with few cells. Researches have showed that CSCs are considered the most likely reason for cancer recurrence and metastasis. Accumulating evidences have showed that traditional Chinese medicine (TCM) has significant effect on CSCs. It could inhibit the proliferation, self-renew, and multidifferentiation of CSCs. We aimed to summarize the theories of CSCs in TCM, the inhibitory effect, and the pathway on CSCs of TCM. This review will provide potential new strategies and alternative perspectives for CSCs treatments and basic research into complementary and alternative medicine.
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spelling pubmed-56463312017-12-11 Review on Research about Traditional Chinese Medicine in Cancer Stem Cell Wang, Yaohan Feng, Li Piao, Bingkui Zhang, Peitong Evid Based Complement Alternat Med Review Article Cancer stem cells (CSCs) are small subpopulations of neoplastic cells within a tumor, which have self-renewal and differentiation abilities and could generate new tumors with few cells. Researches have showed that CSCs are considered the most likely reason for cancer recurrence and metastasis. Accumulating evidences have showed that traditional Chinese medicine (TCM) has significant effect on CSCs. It could inhibit the proliferation, self-renew, and multidifferentiation of CSCs. We aimed to summarize the theories of CSCs in TCM, the inhibitory effect, and the pathway on CSCs of TCM. This review will provide potential new strategies and alternative perspectives for CSCs treatments and basic research into complementary and alternative medicine. Hindawi 2017 2017-10-04 /pmc/articles/PMC5646331/ /pubmed/29234398 http://dx.doi.org/10.1155/2017/4505194 Text en Copyright © 2017 Yaohan Wang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wang, Yaohan
Feng, Li
Piao, Bingkui
Zhang, Peitong
Review on Research about Traditional Chinese Medicine in Cancer Stem Cell
title Review on Research about Traditional Chinese Medicine in Cancer Stem Cell
title_full Review on Research about Traditional Chinese Medicine in Cancer Stem Cell
title_fullStr Review on Research about Traditional Chinese Medicine in Cancer Stem Cell
title_full_unstemmed Review on Research about Traditional Chinese Medicine in Cancer Stem Cell
title_short Review on Research about Traditional Chinese Medicine in Cancer Stem Cell
title_sort review on research about traditional chinese medicine in cancer stem cell
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646331/
https://www.ncbi.nlm.nih.gov/pubmed/29234398
http://dx.doi.org/10.1155/2017/4505194
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