Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure

[Image: see text] Nerve agents and organophosphorus pesticides make a covalent bond with the active site serine of acetylcholinesterase (AChE), resulting in inhibition of AChE activity and toxic symptoms. AChE in red blood cells (RBCs) serves as a surrogate for AChE in the nervous system. Mass spect...

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Detalles Bibliográficos
Autores principales: Dafferner, Alicia J., Schopfer, Lawrence M., Xiao, Gaoping, Cashman, John R., Yerramalla, Udaya, Johnson, Rudolph C., Blake, Thomas A., Lockridge, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646370/
https://www.ncbi.nlm.nih.gov/pubmed/28892361
http://dx.doi.org/10.1021/acs.chemrestox.7b00209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646370/
https://www.ncbi.nlm.nih.gov/pubmed/28892361
http://dx.doi.org/10.1021/acs.chemrestox.7b00209

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