Self-domestication in Homo sapiens: Insights from comparative genomics

This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-d...

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Detalles Bibliográficos
Autores principales: Theofanopoulou, Constantina, Gastaldon, Simone, O’Rourke, Thomas, Samuels, Bridget D., Messner, Angela, Martins, Pedro Tiago, Delogu, Francesco, Alamri, Saleh, Boeckx, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646786/
https://www.ncbi.nlm.nih.gov/pubmed/29045412
http://dx.doi.org/10.1371/journal.pone.0185306
Descripción
Sumario:This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-domestication in Homo sapiens, a process that likely intensified as our species populated its niche. Our analysis lends support to attempts to capture the “domestication syndrome” in terms of alterations to certain signaling pathways and cell lineages, such as the neural crest.

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