Self-domestication in Homo sapiens: Insights from comparative genomics

This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-d...

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Autores principales: Theofanopoulou, Constantina, Gastaldon, Simone, O’Rourke, Thomas, Samuels, Bridget D., Messner, Angela, Martins, Pedro Tiago, Delogu, Francesco, Alamri, Saleh, Boeckx, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646786/
https://www.ncbi.nlm.nih.gov/pubmed/29045412
http://dx.doi.org/10.1371/journal.pone.0185306
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author Theofanopoulou, Constantina
Gastaldon, Simone
O’Rourke, Thomas
Samuels, Bridget D.
Messner, Angela
Martins, Pedro Tiago
Delogu, Francesco
Alamri, Saleh
Boeckx, Cedric
author_facet Theofanopoulou, Constantina
Gastaldon, Simone
O’Rourke, Thomas
Samuels, Bridget D.
Messner, Angela
Martins, Pedro Tiago
Delogu, Francesco
Alamri, Saleh
Boeckx, Cedric
author_sort Theofanopoulou, Constantina
collection PubMed
description This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-domestication in Homo sapiens, a process that likely intensified as our species populated its niche. Our analysis lends support to attempts to capture the “domestication syndrome” in terms of alterations to certain signaling pathways and cell lineages, such as the neural crest.
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spelling pubmed-56467862017-10-30 Self-domestication in Homo sapiens: Insights from comparative genomics Theofanopoulou, Constantina Gastaldon, Simone O’Rourke, Thomas Samuels, Bridget D. Messner, Angela Martins, Pedro Tiago Delogu, Francesco Alamri, Saleh Boeckx, Cedric PLoS One Research Article This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-domestication in Homo sapiens, a process that likely intensified as our species populated its niche. Our analysis lends support to attempts to capture the “domestication syndrome” in terms of alterations to certain signaling pathways and cell lineages, such as the neural crest. Public Library of Science 2017-10-18 /pmc/articles/PMC5646786/ /pubmed/29045412 http://dx.doi.org/10.1371/journal.pone.0185306 Text en © 2017 Theofanopoulou et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Theofanopoulou, Constantina
Gastaldon, Simone
O’Rourke, Thomas
Samuels, Bridget D.
Messner, Angela
Martins, Pedro Tiago
Delogu, Francesco
Alamri, Saleh
Boeckx, Cedric
Self-domestication in Homo sapiens: Insights from comparative genomics
title Self-domestication in Homo sapiens: Insights from comparative genomics
title_full Self-domestication in Homo sapiens: Insights from comparative genomics
title_fullStr Self-domestication in Homo sapiens: Insights from comparative genomics
title_full_unstemmed Self-domestication in Homo sapiens: Insights from comparative genomics
title_short Self-domestication in Homo sapiens: Insights from comparative genomics
title_sort self-domestication in homo sapiens: insights from comparative genomics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646786/
https://www.ncbi.nlm.nih.gov/pubmed/29045412
http://dx.doi.org/10.1371/journal.pone.0185306
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