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Substitutions in conserved regions preceding and within the linker affect activity and flexibility of tRNase Z(L), the long form of tRNase Z
The enzyme tRNase Z, a member of the metallo-β-lactamase family, endonucleolytically removes 3’ trailers from precursor tRNAs, preparing them for CCA addition and aminoacylation. The short form of tRNase Z, tRNase Z(S), functions as a homodimer and is found in all prokaryotes and some eukaryotes. Th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646807/ https://www.ncbi.nlm.nih.gov/pubmed/29045449 http://dx.doi.org/10.1371/journal.pone.0186277 |