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Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D(3) metabolism

RATIONALE: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be vitamin D3 (VD3) deficient, which is associated with more severe disease and increased polyp size. To gain mechanistic insights into these observational studies, we examined the impact of VD3 deficiency...

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Detalles Bibliográficos
Autores principales:	Mulligan, Jennifer K., Pasquini, Whitney N., Carroll, William W., Williamson, Tucker, Reaves, Nicholas, Patel, Kunal J., Mappus, Elliott, Schlosser, Rodney J., Atkinson, Carl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646812/ https://www.ncbi.nlm.nih.gov/pubmed/29045457 http://dx.doi.org/10.1371/journal.pone.0186374

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