Cargando…

Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D(3) metabolism

RATIONALE: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be vitamin D3 (VD3) deficient, which is associated with more severe disease and increased polyp size. To gain mechanistic insights into these observational studies, we examined the impact of VD3 deficiency...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mulligan, Jennifer K., Pasquini, Whitney N., Carroll, William W., Williamson, Tucker, Reaves, Nicholas, Patel, Kunal J., Mappus, Elliott, Schlosser, Rodney J., Atkinson, Carl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646812/ https://www.ncbi.nlm.nih.gov/pubmed/29045457 http://dx.doi.org/10.1371/journal.pone.0186374

Ejemplares similares

C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis
por: Mulligan, Jennifer K., et al.
Publicado: (2018)

25(OH)D Is Effective to Repress Human Cholangiocarcinoma Cell Growth through the Conversion of 25(OH)D to 1α,25(OH)(2)D(3)
por: Chiang, Kun-Chun, et al.
Publicado: (2016)

25(OH)D status: Effect of D(3) supplement
por: Lukaszuk, J. M., et al.
Publicado: (2017)

Lower placental 25-hydroxyvitamin D(3) (25(OH)D(3)) and higher placental CYP27B1 and 25(OH)D(3) ratio in preterm birth
por: Irwinda, Rima, et al.
Publicado: (2020)

Association of Dietary Vitamin D Intake, Serum 25(OH)D(3), 25(OH)D(2) with Cognitive Performance in the Elderly
por: Wang, RuTong, et al.
Publicado: (2021)

Antidepressants differentially related to 1,25-(OH)(2) vitamin D(3) and 25-(OH) vitamin D(3) in late-life depression
por: Oude Voshaar, R C, et al.
Publicado: (2014)

Does Sevelamer Hydrochloride (Renagel) Influence 25(Oh)D3 and 1,25(Oh)2D3 Level in Haemodialysis Patients?
por: Strózecki, Pawel, et al.
Publicado: (2005)

25(OH)D(3) and 1.25(OH)(2)D(3) inhibits TNF-α expression in human monocyte derived macrophages
por: Rafique, Aisha, et al.
Publicado: (2019)

Validation and Determination of 25(OH) Vitamin D and 3-Epi25(OH)D3 in Breastmilk and Maternal- and Infant Plasma during Breastfeeding
por: Gjerde, Jennifer, et al.
Publicado: (2020)

Multiple Sclerosis Patients Show Lower Bioavailable 25(OH)D and 1,25(OH)(2)D, but No Difference in Ratio of 25(OH)D/24,25(OH)(2)D and FGF23 Concentrations
por: Vlot, Mariska C, et al.
Publicado: (2019)

Association among plasma 1,25(OH)(2)D, ratio of 1,25(OH)(2)D to 25(OH)D, and prostate cancer aggressiveness
por: Ramakrishnan, Swathi, et al.
Publicado: (2019)

Effects of 1,25(OH)(2)D(3) and 25(OH)D(3) on C2C12 Myoblast Proliferation, Differentiation, and Myotube Hypertrophy
por: van der Meijden, K., et al.
Publicado: (2016)

25(OH)D(2) Half-Life Is Shorter Than 25(OH)D(3) Half-Life and Is Influenced by DBP Concentration and Genotype
por: Jones, K. S., et al.
Publicado: (2014)

The 25(OH)D3, but Not 1,25(OH)2D3 Levels Are Elevated in IBD Patients Regardless of Vitamin D Supplementation and Do Not Associate with Pain Severity or Frequency
por: Zielińska, Anna, et al.
Publicado: (2021)

Predictors of 25(OH)D half-life and plasma 25(OH)D concentration in The Gambia and the UK
por: Jones, K. S., et al.
Publicado: (2014)

Simultaneous determination of vitamin D metabolites 25(OH)D(3) and 1α,25(OH)(2)D(3) in human plasma using liquid chromatography tandem mass spectrometry
por: Xu, Shan, et al.
Publicado: (2022)

Quantitation of serum 25(OH)D2 and 25(OH)D3 concentrations by liquid chromatography tandem mass spectrometry in patients with diabetes mellitus
por: Lin, Yi-Ching, et al.
Publicado: (2018)

Efficacy of two vitamin D immunoassays to detect 25-OH vitamin D2 and D3
por: Garnett, Emily, et al.
Publicado: (2019)

Without 1α-hydroxylation, the gene expression profile of 25(OH)D(3) treatment overlaps deeply with that of 1,25(OH)(2)D(3) in prostate cancer cells
por: Susa, Takao, et al.
Publicado: (2018)

Metabolic Advantage of 25(OH)D(3) versus 1,25(OH)(2)D(3) Supplementation in Infantile Nephropathic Cystinosis-Associated Adipose Tissue Browning and Muscle Wasting
por: Zhou, Ping, et al.
Publicado: (2022)

25(OH)D and 1,25(OH)D vitamin D fails to predict sepsis and mortality in a prospective cohort study
por: Ratzinger, Franz, et al.
Publicado: (2017)

1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) Signaling Capacity and the Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer (NSCLC): Implications for Use of 1,25(OH)(2)D(3) in NSCLC Treatment
por: Upadhyay, Santosh Kumar, et al.
Publicado: (2013)

Vitamin D (1,25(OH)(2)D3) induces α-1-antitrypsin synthesis by CD4(+) T cells, which is required for 1,25(OH)(2)D3-driven IL-10
por: Dimeloe, Sarah, et al.
Publicado: (2019)

Effects of vitamin D binding protein phenotypes and vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D
por: Sollid, Stina T, et al.
Publicado: (2016)

Bioavailable 25(OH)D but Not Total 25(OH)D Is an Independent Determinant for Bone Mineral Density in Chinese Postmenopausal Women
por: Li, Chenguang, et al.
Publicado: (2016)

Serum 25(OH)D, PTH and Correlates of Suboptimal 25(OH)D Levels in Persons with Chronic Spinal Cord Injury
por: Hummel, Kayla, et al.
Publicado: (2012)

The effects of maternal dietary supplementation of cholecalciferol (vitamin D(3)) and 25(OH)D(3) on sow and progeny performance()
por: Thayer, Morgan T, et al.
Publicado: (2019)

Differential and Overlapping Effects of 20,23(OH)(2)D3 and 1,25(OH)(2)D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)(2)D3
por: Slominski, Andrzej T., et al.
Publicado: (2018)

Association of serum 25(OH) vitamin D(3) concentration with severity of multiple sclerosis
por: Harandi, Ali Amini, et al.
Publicado: (2012)

Occurrence of Vitamin 25(OH)D(3) Insufficiency in Young Women with Metabolic Syndrome
por: Rogal, Karolina, et al.
Publicado: (2011)

The metabolism of 1,25(OH)(2)D(3) in clinical and experimental kidney disease
por: Turner, Mandy E., et al.
Publicado: (2022)

Vitamin D and 1,25(OH)(2)D Regulation of T cells
por: Cantorna, Margherita T., et al.
Publicado: (2015)

25(OH)D(3)-enriched or fortified foods are more efficient at tackling inadequate vitamin D status than vitamin D(3)
por: Guo, Jing, et al.
Publicado: (2018)

Galectin-3 Contributes to the Inhibitory Effect of lα,25-(OH)(2)D(3) on Osteoclastogenesis
por: Gu, Jianhong, et al.
Publicado: (2021)

Oral Supplementation of the Vitamin D Metabolite 25(OH)D(3) Against Influenza Virus Infection in Mice
por: Hayashi, Hirotaka, et al.
Publicado: (2020)

MON-LB74 The Problem of Measuring 1,25(OH)2 Vitamin D in Patients With High Levels of 25(OH) Vitamin D
por: Vieira, Jose Gilberto, et al.
Publicado: (2020)

Circulatory 25(OH)D and 1,25(OH)(2)D as differential biomarkers between multiple system atrophy and Parkinson's disease patients
por: Ogura, Hiromu, et al.
Publicado: (2021)

25(OH)D-but not 1,25(OH)(2)D–Is an independent risk factor predicting graft loss in stable kidney transplant recipients
por: Zeng, Shufei, et al.
Publicado: (2023)

1-25OH(2)D Mediated Hypercalcemia Secondary to DISR From Immune Checkpoint Inhibitors
por: Disanti, Domenic, et al.
Publicado: (2021)

The Paracrine Feedback Loop Between Vitamin D(3) (1,25(OH)(2)D(3)) and PTHrP in Prehypertrophic Chondrocytes
por: Bach, Frances C, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_si2v6ie720ntjdu0pj352fn8u5