Cargando…

The Toll-like receptor 4 antagonist TAK-242 protects against chronic pancreatitis in rats

Chronic pancreatitis is a progressive disease characterized by irreversible morphological changes to the pancreas, typically causing pain and permanent loss of function. It is a poorly understood disease with the pathogenesis remaining unclear. The authors' previous data demonstrated that the i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Long-Fei, Yu, Lei, Wang, Li-Ming, He, Jun-Tao, Sun, Jiang-Li, Wang, Xiao-Bo, Bai, Zheng-Hai, Wang, Hai, Yan, Ting-Lin, Pei, Hong-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646963/ https://www.ncbi.nlm.nih.gov/pubmed/28765897 http://dx.doi.org/10.3892/mmr.2017.7105

Ejemplares similares

TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice
por: Hua, Fang, et al.
Publicado: (2015)

TAK-242, a Toll-Like Receptor 4 Antagonist, Protects against Aldosterone-Induced Cardiac and Renal Injury
por: Zhang, Yide, et al.
Publicado: (2015)

TAK-242, a toll-like receptor 4 antagonist, against brain injury by alleviates autophagy and inflammation in rats
por: Feng, Yan, et al.
Publicado: (2023)

Selective inhibition of Toll-like receptor 4 signaling by the small molecule TAK-242
por: Kawamoto, T, et al.
Publicado: (2006)

Pharmacological Inhibition of Toll-Like Receptor-4 Signaling by TAK242 Prevents and Induces Regression of Experimental Organ Fibrosis
por: Bhattacharyya, Swati, et al.
Publicado: (2018)

Targeting Toll-like receptor 4 with CLI-095 (TAK-242) enhances the antimetastatic effect of the estrogen receptor antagonist fulvestrant on non-small cell lung cancer
por: Fan, S., et al.
Publicado: (2020)

TAK-242 ameliorates contact dermatitis exacerbated by IL-36 receptor antagonist deficiency
por: Fukushima, Hidehiko, et al.
Publicado: (2020)

Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress
por: Gárate, Iciar, et al.
Publicado: (2014)

Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as a new potential anti-rheumatoid arthritis drug
por: Samarpita, Snigdha, et al.
Publicado: (2020)

TAK-242, a specific inhibitor of Toll-like receptor 4 signalling, prevents endotoxemia-induced skeletal muscle wasting in mice
por: Ono, Yuko, et al.
Publicado: (2020)

TAK-242, a novel Toll-like receptor 4 signal transduction inhibitor, protects mice in Escherichia coli-induced and lipoteichoic acid-induced lethality models
por: Ii, M, et al.
Publicado: (2006)

Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model
por: Fellner, Avi, et al.
Publicado: (2017)

Sulfonamide Prodrugs with a Two-Stage Release Mechanism for the Efficient Delivery of the TLR4 Antagonist TAK-242
por: Kostyo, Jessica H., et al.
Publicado: (2022)

TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis
por: Liu, Sujie, et al.
Publicado: (2022)

TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipidinduced inflammation and insulin resistance in muscle cells
por: Hussey, Sophie E., et al.
Publicado: (2012)

TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats
por: Zhong, Xiang, et al.
Publicado: (2019)

Prenatal exposure to TAK242 affects the childhood autism in offspring in animal models of autism spectrum disorder
por: Xu, Xiaoyan, et al.
Publicado: (2017)

TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity
por: Moser, V. Alexandra, et al.
Publicado: (2018)

Inhibition of intimal hyperplasia in murine aortic allografts by administration of a small-molecule TLR4 inhibitor TAK-242
por: Wu, Chuangyan, et al.
Publicado: (2017)

TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway
por: Wang, Jiajia, et al.
Publicado: (2020)

TAK-242 protects against oxygen-glucose deprivation and reoxygenation-induced injury in brain microvascular endothelial cells and alters the expression pattern of lncRNAs
por: Kong, Li-Yun, et al.
Publicado: (2023)

TAK-242 ameliorates epileptic symptoms in mice by inhibiting the TLR4/NF-κB signaling pathway
por: Dong, Jibo, et al.
Publicado: (2022)

Toll-like receptor (TLRs) agonists and antagonists for COVID-19 treatments
por: Liu, Zhi-Mei, et al.
Publicado: (2022)

The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge
por: Younan, Patrick, et al.
Publicado: (2017)

Clinical significance and diagnostic value of serum NSE, CEA, CA19-9, CA125 and CA242 levels in colorectal cancer
por: Luo, Hai, et al.
Publicado: (2020)

Natural Products with Toll-Like Receptor 4 Antagonist Activity
por: Molteni, Monica, et al.
Publicado: (2018)

miR-186 and 326 Predict the Prognosis of Pancreatic Ductal Adenocarcinoma and Affect the Proliferation and Migration of Cancer Cells
por: Zhang, Zheng-liang, et al.
Publicado: (2015)

Comparative study of CA242 and CA19-9 in chronic pancreatitis.
por: Furuya, N., et al.
Publicado: (1996)

CXCR3 antagonist VUF10085 binds to an intrahelical site distinct from that of the broad spectrum antagonist TAK–779
por: Nedjai, Belinda, et al.
Publicado: (2015)

TAK-242 exerts a neuroprotective effect via suppression of the TLR4/MyD88/TRIF/NF-κB signaling pathway in a neonatal hypoxic-ischemic encephalopathy rat model
por: Jiang, Lijun, et al.
Publicado: (2020)

Novel Toll-like receptor-4 antagonist (+)-naloxone protects mice from inflammation-induced preterm birth
por: Chin, Peck Yin, et al.
Publicado: (2016)

Comparative study of CA242 and CA19-9 for the diagnosis of pancreatic cancer.
por: Kawa, S., et al.
Publicado: (1994)

Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1
por: Zou, Yonggang, et al.
Publicado: (2022)

Toll-like receptor 4 gene polymorphisms and susceptibility to colorectal cancer: a meta-analysis and review
por: Sheng, Wang Yan, et al.
Publicado: (2015)

Health Tract, No. 242: Emergencies
Publicado: (1866)

The evolutionary characteristics and structural biology of Gallus toll‐like receptor 21
por: Wu, Hongping, et al.
Publicado: (2017)

Modeling of the Toll-like receptor 3 and a putative Toll-like receptor 3 antagonist encoded by the African swine fever virus
por: Henriques, Elsa S, et al.
Publicado: (2011)

Effect of Pingchuan Formula on Toll-Like Receptors and Dendritic Cells in an Asthmatic Mouse Model
por: Liu, Fei, et al.
Publicado: (2020)

Clinical evaluation of a new serum tumour marker CA 242 in pancreatic carcinoma.
por: Pasanen, P. A., et al.
Publicado: (1992)

Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9
por: Kandimalla, Ekambar R., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vrs290mibn973i4fkeq97nbq86