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Production of bFGF monoclonal antibody and its inhibition of metastasis in Lewis lung carcinoma

Basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor 1 (FGFR1) are associated with drug resistance in lung cancer. In the present study, mouse monoclonal antibodies (mAb) against human bFGF, targeting the binding site of bFGF with FGFR1 were produced, and the antitumor activit...

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Detalles Bibliográficos
Autores principales:	Yang, Yanqing, Luo, Zhenming, Qin, Yiyang, Zhou, Yu, Gong, Longcai, Huang, Jianfang, Wang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646982/ https://www.ncbi.nlm.nih.gov/pubmed/28765892 http://dx.doi.org/10.3892/mmr.2017.7099

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