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Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1

Vascular remodeling is a common complication and pathological basis of hypertension. Transforming growth factor-β1 (TGF-β1)/small mothers against decapentaplegic 3 (Smad3) is considered a potential therapeutic target for vascular remodeling in hypertension. The present study aimed to demonstrate the...

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Detalles Bibliográficos
Autores principales: Shang, Peijin, Liu, Tianlong, Liu, Wenxing, Li, Yuwen, Dou, Fang, Zhang, Yikai, Sun, Lijuan, Zhang, Tiejun, Zhu, Zhihui, Mu, Fei, Ding, Yi, Wen, Aidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646990/
https://www.ncbi.nlm.nih.gov/pubmed/28791353
http://dx.doi.org/10.3892/mmr.2017.7177

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