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Melatonin counteracts cobalt nanoparticle-induced cytotoxicity and genotoxicity by deactivating reactive oxygen species-dependent mechanisms in the NRK cell line

Cobalt nanoparticles (CoNPs) released from metal-on-metal implants have caused considerable concern. Oxidative stress is associated with the mechanism underlying cobalt-induced cytotoxicity and genotoxicity. The indolamine melatonin exhibits protective effects against damage induced by metals. The p...

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Detalles Bibliográficos
Autores principales:	Liu, Yake, Yang, Xiaoyou, Wang, Wei, Wu, Xuefei, Zhu, Hai, Liu, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647000/ https://www.ncbi.nlm.nih.gov/pubmed/28849220 http://dx.doi.org/10.3892/mmr.2017.7309

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