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Atorvastatin increases Fads1, Fads2 and Elovl5 gene expression via the geranylgeranyl pyrophosphate-dependent Rho kinase pathway in 3T3-L1 cells

Numerous clinical studies have reported that statins increase the plasma concentration of arachidonic acid, which is an ω-6 long-chain polyunsaturated fatty acid (LCPUFA), and decrease the concentrations of eicosapentaenoic acid and docosahexaenoic acid, which are ω-3 LCPUFAs. These findings indicat...

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Detalles Bibliográficos
Autores principales:	Ishihara, Noriko, Suzuki, Sawako, Tanaka, Shou, Watanabe, Yasuhiro, Nagayama, Daiji, Saiki, Atsuhito, Tanaka, Tomoaki, Tatsuno, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647059/ https://www.ncbi.nlm.nih.gov/pubmed/28765914 http://dx.doi.org/10.3892/mmr.2017.7141

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