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Optimizing Thiopurine Therapy in Inflammatory Bowel Disease Among 2 Real-life Intercept Cohorts: Effect of Allopurinol Comedication?

BACKGROUND: Thiopurines (azathioprine and mercaptopurine) are frequently used immunosuppressive drugs to maintain remission in patients with inflammatory bowel disease. Half of the conventional thiopurine-derivative users have to discontinue treatment within 5 years, mainly because of intolerable ad...

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Detalles Bibliográficos
Autores principales: Meijer, Berrie, Seinen, Margien L., van Egmond, Remco, Bouma, Gerd, Mulder, Chris J. J., van Bodegraven, Adriaan A., de Boer, Nanne K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647119/
https://www.ncbi.nlm.nih.gov/pubmed/28617756
http://dx.doi.org/10.1097/MIB.0000000000001168