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SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase

Berardinelli-Seip congenital lipodystrophy 2 (BSCL2) is caused by loss-of-function mutations in SEIPIN, a protein implicated in both adipogenesis and lipid droplet expansion but whose molecular function remains obscure. Here, we identify physical and functional interactions between SEIPIN and micros...

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Detalles Bibliográficos
Autores principales: Pagac, Martin, Cooper, Daniel E., Qi, Yanfei, Lukmantara, Ivan E., Mak, Hoi Yin, Wu, Zengying, Tian, Yuan, Liu, Zhonghua, Lei, Mona, Du, Ximing, Ferguson, Charles, Kotevski, Damian, Sadowski, Pawel, Chen, Weiqin, Boroda, Salome, Harris, Thurl E., Liu, George, Parton, Robert G., Huang, Xun, Coleman, Rosalind A., Yang, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647143/
https://www.ncbi.nlm.nih.gov/pubmed/27806294
http://dx.doi.org/10.1016/j.celrep.2016.10.037