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Perisomatic changes in h-channels regulate depressive behaviors following chronic unpredictable stress

Chronic stress can be a precipitating factor in the onset of depression. Lentiviral-mediated knockdown of HCN1 protein expression and reduction of functional I(h) produce antidepressant behavior. However, whether h-channels are altered in an animal model of depression is not known. We found that per...

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Detalles Bibliográficos
Autores principales:	Kim, C S, Brager, D H, Johnston, D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647208/ https://www.ncbi.nlm.nih.gov/pubmed/28416809 http://dx.doi.org/10.1038/mp.2017.28

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