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Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels
Tetrameric coiled-coil structures are present in many ion channels, often adjacent to a calmodulin (CaM) binding site, although the relationship between the two is not completely understood. Here we examine the dynamic properties of the ABCD domain located in the intracellular C-terminus of tetramer...
Autores principales: | Alaimo, Alessandro, Nuñez, Eider, Aivar, Paloma, Fernández-Orth, Juncal, Gomis-Perez, Carolina, Bernardo-Seisdedos, Ganeko, Malo, Covadonga, Villarroel, Alvaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647379/ https://www.ncbi.nlm.nih.gov/pubmed/29044210 http://dx.doi.org/10.1038/s41598-017-13811-4 |
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