Facilitating identification of minimal protein binding domains by cross-linking mass spectrometry

Characterization of protein interaction domains is crucial for understanding protein functions. Here we combine cross-linking mass spectrometry (XL-MS) with deletion analysis to accurately locate minimal protein interaction domains. As a proof of concept, we investigated in detail the binding interf...

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Detalles Bibliográficos
Autores principales: Liu, Qingyang, Remmelzwaal, Sanne, Heck, Albert J. R., Akhmanova, Anna, Liu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647383/
https://www.ncbi.nlm.nih.gov/pubmed/29044157
http://dx.doi.org/10.1038/s41598-017-13663-y

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