microRNA-181b is increased in cystic fibrosis cells and impairs lipoxin A(4) receptor-dependent mechanisms of inflammation resolution and antimicrobial defense

The involvement of microRNA (miR) in cystic fibrosis (CF) pathobiology is rapidly emerging. We previously documented that miR-181b controls the expression of the ALX/FPR2 receptor, which is recognized by the endogenous proresolution ligand, lipoxin (LX)A(4). Here, we examined whether the miR-181b-AL...

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Detalles Bibliográficos
Autores principales: Pierdomenico, Anna Maria, Patruno, Sara, Codagnone, Marilina, Simiele, Felice, Mari, Veronica Cecilia, Plebani, Roberto, Recchiuti, Antonio, Romano, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647414/
https://www.ncbi.nlm.nih.gov/pubmed/29044225
http://dx.doi.org/10.1038/s41598-017-14055-y

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