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IRE1α/XBP1s branch of UPR links HIF1α activation to mediate ANGII-dependent endothelial dysfunction under particulate matter (PM) 2.5 exposure

Short- and long-term exposure to particulate matter (PM) 2.5 instigates adverse health effect upon the cardiovascular (CV) system. Disclosing the molecular events by which PM2.5 evokes CV injuries is essential in developing effective risk-reduction strategy. Here we found that rats after intratrache...

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Detalles Bibliográficos
Autores principales: Xu, Xiuduan, qimuge, Aodeng, Wang, Hongli, Xing, Chen, Gu, Ye, Liu, Shasha, Xu, Huan, Hu, Meiru, Song, Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647447/
https://www.ncbi.nlm.nih.gov/pubmed/29044123
http://dx.doi.org/10.1038/s41598-017-13156-y