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Context memory formation requires activity-dependent protein degradation in the hippocampus

Numerous studies have indicated that the consolidation of contextual fear memories supported by an aversive outcome like footshock requires de novo protein synthesis as well as protein degradation mediated by the ubiquitin–proteasome system (UPS). Context memory formed in the absence of an aversive...

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Detalles Bibliográficos
Autores principales: Cullen, Patrick K., Ferrara, Nicole C., Pullins, Shane E., Helmstetter, Fred J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647928/
https://www.ncbi.nlm.nih.gov/pubmed/29038220
http://dx.doi.org/10.1101/lm.045443.117