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Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition

The mechanistic/mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates cellular signals from the nutrient and energy status to act, namely, on the protein synthesis machinery. While major advances have emerged regarding the regulators and effects of the mTOR sign...

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Detalles Bibliográficos
Autores principales: Marques-Ramos, Ana, Candeias, Marco M., Menezes, Juliane, Lacerda, Rafaela, Willcocks, Margaret, Teixeira, Alexandre, Locker, Nicolas, Romão, Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648038/
https://www.ncbi.nlm.nih.gov/pubmed/28821580
http://dx.doi.org/10.1261/rna.063040.117